Here’s a clear summary of prostate cancer treatments by stage.
Stage I – Early / Very Low Risk
Cancer is small, confined to the prostate, and often slow-growing.
Typical options:
Active surveillance (watchful waiting) – most common
Surgery (radical prostatectomy) – if patient is younger or prefers active treatment
Radiation therapy – an alternative to surgery
Stage II – Localized (Still in the Prostate)
Tumor is larger but still confined within the prostate.
Typical options:
Surgery (robotic or open prostatectomy)
External beam radiation or brachytherapy
Hormone therapy may be added to radiation in some cases
Active surveillance is still possible for low-risk cases
Stage III – Locally Advanced
Cancer has spread just outside the prostate (e.g., to the seminal vesicles) but not to lymph nodes or distant organs.
Typical options:
Radiation therapy + hormone therapy (combination)
Surgery (in select cases) followed by radiation if needed
Stage IV – Advanced / Metastatic
Cancer has spread to lymph nodes, bones, or other organs.
Typical options:
Hormone therapy (ADT) – first-line treatment
Chemotherapy (e.g., docetaxel)
Targeted therapy (e.g., PARP inhibitors for BRCA mutations)
Immunotherapy (e.g., sipuleucel-T, pembrolizumab)
Radiation for symptom relief (e.g., bone pain)
Recurrent or Resistant Prostate Cancer
If the cancer returns or becomes resistant to hormone therapy:
Next-generation hormone blockers (enzalutamide, abiraterone)
Chemotherapy or targeted therapy
Clinical trials for novel treatments
